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Qatari side clinched a 6-2 victory over Uzbekistan vice-champions. Ibrahim Ibrahim recorded a brace, while Al Haydos, Belhadj, Hassan and Grafite were on target for Al Sadd.
Damir Kojaševic and Jasur Hasanov netted goals for Lokomotiv Tashkent in the match.
After three matches Lokomotiv is in the bottom of the Group C with just one point.